IMR Press / EJGO / Volume 30 / Issue 6 / pii/2009160

European Journal of Gynaecological Oncology (EJGO) is published by IMR Press from Volume 40 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on as a courtesy and upon agreement with S.O.G.

Original Research

Intraoperative assessment of epithelial and non-epithelial ovarian tumors: a 7-year review

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1 Department of Pathology, University of Athens (Greece)
2 Department of Pathology, Iaso Maternity Hospital (Greece)
3 Department of Obstetrics and Gynecology, University of Ioannina (Greece)
4 Department of Gynecological Oncology, Iaso Maternity Hospital (Greece)
5 1st Department of Obstetrics and Gynecology, University of Athens (Greece)
Eur. J. Gynaecol. Oncol. 2009, 30(6), 657–660;
Published: 10 December 2009

Objective: To determine the accuracy of frozen section diagnosis of ovarian tumors and to discuss discrepant diagnostic cases. Methods: 932 ovarian tumors were submitted for frozen section examination. Cases with a significant diagnostic discrepancy between the intraoperative and the final histological diagnosis were reviewed. Results: The sensitivity of frozen section diagnosis for benign, borderline and malignant epithelial tumors was 98.82%, 98.97% and 87.66% and the specificity 98.01%, 97.06% and 100%, respectively. There were 27 cases with diagnostic discrepancy. All non teratomatous sex cord/stromal and germ cell tumors were correctly diagnosed while a diagnostic discrepancy was observed in teratomatous tumors. Conclusion: Frozen section diagnosis is a reliable method for the surgical management of an ovarian mass. Nevertheless, care should be taken for large tumors measuring > 20 cm in diameter, particularly when the intraoperative diagnosis reveals an epithelial borderline tumor or a teratomatous tumor with an extensive neural component. 

Frozen section
Intraoperative assessment
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