IMR Press / EJGO / Volume 29 / Issue 5 / pii/1631004257593-320630301

European Journal of Gynaecological Oncology (EJGO) is published by IMR Press from Volume 40 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on as a courtesy and upon agreement with S.O.G.

Original Research
Platin sensitivity and long-term survival in Stage III epithelial ovarian cancer patients
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1 Department of Obstetrics and Gynecology, Gynecologic Oncology Unit, E. Wolfson Medical Center, Holon, Israel, Tel Aviv University, Sackler Faculty of Medicine, Tel Aviv (Israel)
Eur. J. Gynaecol. Oncol. 2008, 29(5), 473–475;
Published: 10 October 2008

Purpose: The aim of the present study was to assess the effect of platin sensitivity on long-term survival of Stage III epithelial ovarian cancer (EOC) patients. Methods: The records of all histologically confirmed Stage III EOC and PPC patients diagnosed during 1995- 2006 were reviewed. A comparison of selected characteristics was made between long-term (> 5 years) and short-term (< 3 years) survivors. Results: Among 58 Stage III patients, 20 had long-term and 18 short-term survival. The rate of platin sensitive patients in longterm survivors was significantly higher than in short-term survivors (95.0% vs 27.8%, p < 0.001). The sensitivity and specificity of platin sensitivity for long-term survival was 95% and 72.2%, respectively, and the positive and negative predictive value was 79.2% and 92.8%, respectively. No statistically significant difference between the groups was found with regard to other selected characteristics. Conclusion: The rate of platin sensitive patients was significantly higher among long-term survivors than among short-term survivors but the specificity and positive predictive value of platin sensitivity for long-term survival prediction were relatively low precluding its practical clinical use.
Epithelial ovarian cancer
Platin sensitivity
Primary peritoneal carcinoma
Long-term survival
Short-term survival
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