IMR Press / EJGO / Volume 29 / Issue 2 / pii/1630995404711-952234530

European Journal of Gynaecological Oncology (EJGO) is published by IMR Press from Volume 40 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on as a courtesy and upon agreement with S.O.G.

Case Report
Metastatic breast carcinoma initially presenting as acute cholecystitis: a case report and review of the literature
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1 First Department of Propaedeutic Surgery, Hippocrateion Hospital, Athens Medical School, Athens (Greece)
Eur. J. Gynaecol. Oncol. 2008, 29(2), 179–181;
Published: 10 April 2008

Introduction: The gallbladder is an infrequent site of metastatic malignant disease. Although malignant melanoma, renal cell and cervical carcinoma have been documented, breast carcinoma has rarely been reported to metastasize in the gallbladder. Case Report: We describe such a case that manifested as acute cholecystitis and was incidentally recognized after cholecystectomy, in an otherwise disease-free 46-year-old female who had undergone mastectomy for breast cancer two years before. The patient was subjected to adjuvant chemotherapy, but unfortunately died just a year after diagnosis because of generalized peritoneal seeding of the tumor. Discussion: Metastatic gallbladder involvement is rare, especially in cases of primary breast carcinoma, usually leading to symptoms of abdominal pain, mimicking acute or chronic cholecystitis. Thus, abdominal pain in a patient with a previous history of breast carcinoma should raise suspicion of gallbladder metastasis.
Metastatic breast cancer
Acute cholecystitis
Ductal breast carcinoma
Gallbladder metastasis
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