IMR Press / EJGO / Volume 28 / Issue 5 / pii/2007198

European Journal of Gynaecological Oncology (EJGO) is published by IMR Press from Volume 40 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on as a courtesy and upon agreement with S.O.G.

Case Report

Salivary duct carcinoma presenting with vaginal metastasis: case report

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1 Department of Pathology, London Health Science Center, London, Canada
2 Department of Laboratory Medicine. St. Michael's Hospital, Toronto, Canada
Eur. J. Gynaecol. Oncol. 2007, 28(5), 415–417;
Published: 10 October 2007

Vaginal cancer represents about 1-2% of the genital tract malignancies. Most cases represent metastasis from the cervix, endometrium or colon. Metastasis of salivary duct carcinoma to the vagina has not been previously reported. Salivary duct carcinoma (SDC) is a rare, highly aggressive tumor that most often involves the parotid gland. On presentation, SDC is metastasized to the regional lymph nodes in about 40% of cases. We report a case of metastatic salivary duct carcinoma presenting as a vaginal mass with bleeding. Diagnosis was confirmed by the histological appearance in addition to immunohistochemistry. To our knowledge this is the first reported case of vaginal metastasis from SOC. Small-sized primaries might be ignored by the patient, specially in the older age group, probably due to lack of manifesting symptoms like pain and bleeding. Some cancers, like SDC, have various histologic patterns in different areas of the tumor. Careful examinations of multiple sections, in addition to an immunohistochemical panel, and histologic comparison of all lesions are keys to a correct diagnosis.

Salivary tumors
Salivary duct carcinoma
Salivary gland
Vaginal cancer
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