IMR Press / EJGO / Volume 28 / Issue 3 / pii/2007157

European Journal of Gynaecological Oncology (EJGO) is published by IMR Press from Volume 40 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on as a courtesy and upon agreement with S.O.G.

Case Report

5-Fluorouracil cardiotoxicity complicating treatment of Stage IIB cervical cancer - case report

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1 Indiana Women's Oncology, St. Vincent Hospitals, Indianapolis, IN, USA
2 The Care Group, Division of Cardiology St. Vincent Hospitals, Indianapolis, IN, USA
Eur. J. Gynaecol. Oncol. 2007, 28(3), 235–235;
Published: 10 June 2007

A 31-year-old female was found to have FIGO Stage IIB squamous cell carcinoma of the cervix. The patient began her prescribed radiation therapy and 5-fluorouracil radio-sensitizing chemotherapy. During the first day of infusion, she began having severe shortness of breath. Cardiac evaluation revealed acute congestive heart failure with a cardiac ejection fraction of 19%. Radiation was continued without chemotherapy. Four years later, the patient is alive and well with an ejection fraction of 53%.

5-Fluorouracil cardiotoxicity
Cervical cancer
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