IMR Press / EJGO / Volume 28 / Issue 3 / pii/2007156

European Journal of Gynaecological Oncology (EJGO) is published by IMR Press from Volume 40 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on as a courtesy and upon agreement with S.O.G.

Case Report

Bilateral Brenner tumor with endometrial adenocarcinoma in a postmenopausal woman

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1 Department of Gynaecology, Perinatology and Child Welfare, II Faculty of Medicine and Surgery, “La Sapienza” University, Rome, Italy
2 Department of Clinical Pathology, Operative Unit of Pathology, ASL 9, Macerata, Italy
Eur. J. Gynaecol. Oncol. 2007, 28(3), 233–234;
Published: 10 June 2007

Brenner tumor is a rare ovarian neoplas which is generally monolateral, ore rarely bilateral, and often associated with endometrial disorders related to oestrogenic production. However, there is no considerable evidence that the possible oestrogenic production of this tumor may be the cause of endometrial disorders. A case of bilateral Brenner tumor with endometrial adenocarcinoma in a postmenopausal woman is presented and the features are briefly discussed, with the conclusion that hormone-producing Brenner tumors may exert their promoter effect on the development of endometrial carcinoma causing an imbalance in the oestrogen and progesterone ratio rather than producing a large amount of oestrogen.

Brenner tumor
Endometrial adenocarcinoma
Oestrogen production
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