IMR Press / EJGO / Volume 28 / Issue 3 / pii/2007151

European Journal of Gynaecological Oncology (EJGO) is published by IMR Press from Volume 40 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on as a courtesy and upon agreement with S.O.G.

Original Research

Investigation of Keyes skin biopsy instrument for cervical biopsy procedures versus Kevorkian biopsy forceps

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1 Department of Obstetrics and Gynecology, Zeynep Kamil Women's and Children's Hospital, Istanbul, Turkey
2 Department of Pathology, Zeynep Kamil Women's and Children's Hospital, Istanbul, Turkey
Eur. J. Gynaecol. Oncol. 2007, 28(3), 214–216;
Published: 10 June 2007

Objective: We aimed to investigate the utility and efficacy of the Keyes skin biopsy instrument for cervical biopsy procedures. Material and Methods: A prospective clinical trial was conducted on 50 women with cervical lesions. Colposcopy-guided cervical biopsies were collected using a Keyes biopsy punch and a Kevorkian biopsy forceps and the two methods were compared with defin­itive histopathological examination of the specimens obtained by the loop electrosurgical excision procedure (LEEP), conization or hysterectomy. Results: There were no differences in speed of collection, diagnostic value of specimens, complication rates, or sample quality. The sensitivity, specificity, positive and negative predictivity of specimens were all 100% for both methods. Conclusions: The Keyes biopsy punch was found to be a safe, rapid and accurate diagnostic tool in cervical biopsy procedures. Based on the results of this study, the use of a Keyes punch instrument can be recommended as an alternative to other cervical biopsy methods.

Keyes biopsy instrument
Cervical biopsy
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