IMR Press / EJGO / Volume 28 / Issue 1 / pii/2007101

European Journal of Gynaecological Oncology (EJGO) is published by IMR Press from Volume 40 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with S.O.G.

Distinguished Expert Series

Molecular markers of miscellaneous primary and metastatic tumors of the uterine cervix

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1 Cancer Biology Research Institute, South Dakota Health Research Foundation and Department of Obstetrics and Gynecology, USA
2 Department of Biological and Environmental Sciences, University of the District of Columbia, Washington, USA
3 Department of Laboratory Medicine, Sanford School of Medicine, the University of South Dakota, USA
4 Analytic Epidemiology Research Branch, Epidemiology and Genetics Research Program, Division of Cancer Control and Population Sciences, National Cancer Institute, Bethesda, MD, USA
Eur. J. Gynaecol. Oncol. 2007, 28(1), 5–14;
Published: 10 February 2007
Abstract

Miscellaneous primary tumors of the uterine cervix are rare. Markers which can be utilized to detect these tumors are very few and in most cases, have not been clinically validated. The information provided in this article will help in developing strategies to discover novel markers and initiate translational research in this ignored area. Based on the reported studies, cytokeratin markers are common in many tumors and few of these rare cancers demonstrate human papilloma-virus (HPV) and Epstein Bar virus (EBY) infection. Due to the very low prevalence of these tumors, epidemiological studies have not been conducted and the etiology of these tumors is largely unknown.

Keywords
Uterine cervix
Rare tumors
Markers
Metastatic
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