IMR Press / EJGO / Volume 27 / Issue 6 / pii/2006246

European Journal of Gynaecological Oncology (EJGO) is published by IMR Press from Volume 40 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on as a courtesy and upon agreement with S.O.G.

Original Research

Paget’s disease of the vulva - a review of our experience

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1 Institute of Gynecology and Obstetrics, Clinical Center of Serbia, Belgrade, Serbia and Montenegro
Eur. J. Gynaecol. Oncol. 2006, 27(6), 611–612;
Published: 10 December 2006

Objective: The aim of our study was to review our experience with Paget’s disease of the vulvar relative to initial examination, treatment and oncological outcome. Methods: Ten women with extramammary Paget’s diseases of the vulva were treated during the 10-year period. The charts of these patients were reviewed and data were collected regarding patient demographics, symptoms, previous Paget's disease, surgical treatments and time to recurrence. Results: Eight women (80%) were treated with wide local excision or partial vulvectomy, and two patients (20%) required radical resection for invasive adenocarcinoma. The group of women who had invasive diseases also underwent inquinofemoral lym­phadenectomy and no lymphatic metastases were noted. Three women (30%) experienced recurrence. The mean time to relapse was 30 months (range 3-88 months). Conclusion: Recurrence is very common and long-term monitoring is recommended with careful examination of any abnormal vulvar lesion.

Paget's disease
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