IMR Press / EJGO / Volume 27 / Issue 6 / pii/2006245

European Journal of Gynaecological Oncology (EJGO) is published by IMR Press from Volume 40 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with S.O.G.

Original Research

Results on the treatment of uterine cervix cancer: ten years experience

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1 4th Department of Obstetrics and Gynecology, Aristotles University of Thessaloniki, Hippocrates General Hospital, Thessaloniki, Greece
2 Department of Radiotherapy “Papageorgiou” General Hospital, Thessaloniki, Greece
3 1st Department of Obstetrics and Gynecology, Aristotles University of Thessaloniki, “Papageorgiou” General Hospital, Thessaloniki, Greece
Eur. J. Gynaecol. Oncol. 2006, 27(6), 607–610;
Published: 10 December 2006
Abstract

The aim of the study is to present our experience in the treatment of uterine cervix cancer over the last decade. This is a retrospective study of 90 patients with cervical cancer treated in a University Department of Obstetrics and Gynecology from 1993 to 2002. After the disease was histologically confirmed and staged the patients were treated according to stage with surgery (S) radiotherapy (RT), RT alone or Chemoradiaton (C-RT). The course of the disease and follow-up was traced from patient notes and after a structured telephone questionnaire. Mean age of patients was 48 ± 14.3 years (29-84). Nine of 90 patients (10%) were lost to follow-up. FIGO (1994) staging was I in 50% of patients, II in 33.5%, III in 13.5% and IV in 3%. The size of tumor was ≤4 cm in 75%. Of the tumors 87% were of squa­mous histology and 13% adenocarcinomas. Patients were treated with cone biopsy (5.5%), type I hysterectomy pelvic RT (10%), radical (type II-III) hysterectomy and pelvic lymphadenectomy ± radiotherapy (41 %), RT alone in 38% and C-RT in 5.5%. Inci­dence of complications after surgery was 19.5% and after RT 12.5%. Mean follow-up was 41 ± 19 months (6-110). Five-year sur­vival in Stage I was 84%, Stage II 64% and Stage III 40%. A single patient with Stage IV disease is alive with disease after two years. In conclusion uterine cervical cancer has improved survival because of early diagnosis. Treatment should be individualized according to the status of disease. Surgery and RT had similar rates of complications.

Keywords
Uterine cervical cancer
Treatment
Radical hysterectomy
Radiotherapy
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