IMR Press / EJGO / Volume 27 / Issue 4 / pii/2006185

European Journal of Gynaecological Oncology (EJGO) is published by IMR Press from Volume 40 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on as a courtesy and upon agreement with S.O.G.

Original Research

Serum CA125 level modifications in women undergoing repeated IVF cycles

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1 Department of Experimental Medicine, University of L'Aquila, Italy
Eur. J. Gynaecol. Oncol. 2006, 27(4), 353–358;
Published: 10 August 2006

In the present paper, serum CA 125 modifications in patients undergoing their first IVF cycle were compared with those of patients in their second attempt. A significant increase of this marker was detected in each group of patients at day 14 after embryo trans­fer. However, the level of CA 125 monitored in the patients in their second attempt was significantly higher than that determined in patients undergoing their first ovarian stimulation. This condition does not influence either ovarian response or oocyte and embryo quality. Moreover similar IVF outcome was obtained. Therefore we propose that patients undergoing repeated assisted reproductive technology (ART) cycles may suffer from ovarian surface epithelial damage and/or altered cellular growth rate.

Ovarian stimulation
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