IMR Press / EJGO / Volume 27 / Issue 1 / pii/2006103

European Journal of Gynaecological Oncology (EJGO) is published by IMR Press from Volume 40 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on as a courtesy and upon agreement with S.O.G.

Original Research

Primary fallopian tube carcinoma: a retrospective clinicopathologic study

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1 Department of Gynecologic Oncology, Roswell Park Cancer Institute, Buffalo, NY, USA
2 Department of Biostatics, Roswell Park Cancer Institute, Buffalo, NY, USA
Eur. J. Gynaecol. Oncol. 2006, 27(1), 16–18;
Published: 10 February 2006

Introduction: Primary fallopian tube carcinoma is a rare tumor. The aim of this study was to evaluate clinical characteristics and management of fallopian tube malignancies at a large tertiary care cancer institute. Methods: A retrospective review of the Tumor Registry was conducted to identify all primary fallopian tube carcinomas between 1980 and 200 I. Medical charts were retrospectively reviewed. Primary endpoints were overall survival and disease recurrence. Results: Thirty-five patients had histology consistent with fallopian tube carcinoma. The median age at diagnosis was 56 years The most common signs or symptoms were abnormal vaginal bleeding (29%) and abdominal/pelvic mass (26%). The most common histology was adenocarcinoma in 16 (46%) patients. Five patients (14%) were Stage I, seven patients (20%) Stage II, 17 patients (49%) Stage III and six patients (17%) Stage IV. Thirty-two (91 %) patients received adjuvant chemotherapy and 77% received plat­inum-based chemotherapy. Twenty-seven (77%) patients underwent second-look surgery, of which 17 patients (63%) were positive for disease. The 5-year survival rate was 64% for Stage I, 42% for Stage II, 32% for Stage III, and 17% for Stage IV. Conclusions: Fallopian tube malignancies are rare and carry a poor prognosis. More extensive research needs to be performed to have definitive etiologic, diagnostic and treatment guidelines.

Fallopian tube cancer
Second-look surgery
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