IMR Press / EJGO / Volume 26 / Issue 5 / pii/2005231

European Journal of Gynaecological Oncology (EJGO) is published by IMR Press from Volume 40 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on as a courtesy and upon agreement with S.O.G.

Original Research

Gherlin expression in women with polycystic ovary syndrome - a preliminary study

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1 Department of Molecular Virology, Poznan Adam Mickiewicz University, Poznań (Poland)
2 Department of Gynecological Endocrinology, Poznan University of Medical Sciencies, Poznań (Poland)
3 Department of Animal Physiology, Poznań Adam Mickiewicz University, Poznań (Poland)
Eur. J. Gynaecol. Oncol. 2005, 26(5), 553–556;
Published: 10 October 2005

The etiology and pathogenesis of polycystic ovary syndrome (PCOS) is still unknown. Using real-time PCR, we detected that polycystic ovaries showed almost ten times lower expression of ghrelin mRNA than normal ovaries, whereas the mRNA levels in blood cells were similar in both study groups. This suggests that the presence of ghrelin in PCOS and normal ovaries may have an autocrine/paracrine modulatory effect on ovary functions and local significance in the etiology of PCOS.

Ghrelin expression
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