IMR Press / EJGO / Volume 26 / Issue 5 / pii/2005220

European Journal of Gynaecological Oncology (EJGO) is published by IMR Press from Volume 40 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on as a courtesy and upon agreement with S.O.G.

Original Research

Adenofibromasarcoma originating from a mural nodule of ovarian serous cystadenoma

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1 Department of Obstetrics and Gynecology, Kobe University Graduate School of Medicine, Kobe (Japan)
2 Division of Molecular Pathology, Kobe University Graduate School of Medicine, Kobe (Japan)
Eur. J. Gynaecol. Oncol. 2005, 26(5), 511–513;
Published: 10 October 2005

A 83-year-old woman received bilateral salpingo-oophorectomy and hysterectomy due to a provisional diagnosis of ovarian cystic tumor. The tumor had a unilocular cystic cavity demonstrating serous cystadenoma and a solid mural nodule representing a bipha­sic pattern with mesenchymal and glandular components. The glandular elements were composed of benign serous cells, whereas the mesenchymal components consisted of an admixture of fibromatous stromal cells without atypia and sarcomatous overgrowth. The area of transition from a fibromatous component to sarcomatous overgrowth was identified. After a 2-year follow-up, there were no signs of tumor recurrence or systemic disease. To the authors' knowledge, this is the first reported case of adenofibrosarcoma originating from a mural nodule of ovarian serous cystadenoma.

Adenofibromasarcoma mural nodule serous tumor ovary
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