IMR Press / EJGO / Volume 26 / Issue 5 / pii/2005218

European Journal of Gynaecological Oncology (EJGO) is published by IMR Press from Volume 40 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on as a courtesy and upon agreement with S.O.G.

Original Research

Epidemiology of malignant breast tumors in the province of Sassari (Sardinia, Italy) in the period 1992-2002

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1 Institute of Pathologic Anatomy, University of Sassari, Sassari (Italy)
2 Multizonal Epidemiologic Observational Center, Azienda USL 1, Sassari (Italy)
3 Department of Pharmacology, Gynecology and Obstetrics, University of Sassari, Sassari (Italy)
4 Institute of Biomolecular Chemistry, C.N.R., Sassari (Italy)
Eur. J. Gynaecol. Oncol. 2005, 26(5), 505–508;
Published: 10 October 2005

The aim of this study was to evaluate the incidence of malignant breast tumors in the Province of Sassari, Sardinia (Italy) in the period 1992-2002 and to report the variations in comparison to the 1974-1985 period. The analysis of our data showed that the overall number of malignant breast tumors was more than doubled from I, 139 cases in the period 1974-1985 to the 2,735 cases in the period 1992-2002, and the mean rate/I 00,000 changed from 43.4 to 106.0. The incidence in the age classes 45-64 years, which were at enhanced risk for breast cancer, was globally increased, changing from 143.6/100,000 to 198.7/100,000. On the other hand, the incidence in the youngest age classes (30-34 yrs) was reduced from 59.5% to 27.0%. The analysis of the histotypes showed a relative reduction of ductal carcinoma in the period 1992-2002 in comparison to the previous period I 974-1985 (65.2% vs 82.0%) whereas the incidence of anaplastic forms increased in advanced ages of life. We reported an important reduction of TO tumors from 3.4% to 0.1 %. These data could be due to the low diffusion of screening programs in Sardinia. Tumor metastases were more fre­quent in advanced age classes. In condusion, the worrying data of the strong reduction of TO cases, the increased age of first diagnosis and the advanced forms with positive nodal . metastases showed that the prevention program has not been yet well organized.

Malignant breast tumors
Province of Sassari (Sardinia
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