IMR Press / EJGO / Volume 25 / Issue 5 / pii/2004238

European Journal of Gynaecological Oncology (EJGO) is published by IMR Press from Volume 40 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on as a courtesy and upon agreement with S.O.G.

Original Research

Cytogenetic abnormalities in serous papillary adenocarcinoma of the ovary

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1 Obstetrics and Gynecology Clinic, Ankara Numune Education and Research Hospital, Ankara (Turkey)
2 Department of Medical Biology and Genetics, Baskent University, Ankara (Turkey)
Eur. J. Gynaecol. Oncol. 2004, 25(5), 585–586;
Published: 10 October 2004

Purpose of investigation: Epithelial ovarian tumors are usually mucinous or serous type, affecting nearly I% of women during their lifetime. They may be regarded as benign, borderline or invasive according to pathological examination. Karyotypes of the tumor provide critical information about both the genetic predisposition and the stage of the tumor. We aimed to investigate the cor­relation between karyotype findings and the stage of the serous papillary tumors of the ovary. Methods: Tissue cultures were set up from 15 serous papillary adenocarcinoma samples of different stages and examined cyto­genetically. Results: The most common chromosome abnormalities included both numerical and structural abnormalities of chromosomes 1, 3, 6, 7, 8, 11, 21, 22 and X. Conclusion: Karyotypes became more complex, as expected, with the later stages.

Serous papillary ovarian cancer
Cytogenetic abnormality
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