IMR Press / EJGO / Volume 25 / Issue 3 / pii/2004189

European Journal of Gynaecological Oncology (EJGO) is published by IMR Press from Volume 40 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on as a courtesy and upon agreement with S.O.G.

Case Report

Primitive neuroectodermal tumor (PNET) of the uterine isthmus

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1 Department of Pathology, Hippokrateio General Hospital, Thessaloniki (Greece)
2 1st Department of Obstetrics and Gynaecology, Aristotle University of Thessaloniki, Hippokrateio General Hospital, Thessaloniki (Greece)
Eur. J. Gynaecol. Oncol. 2004, 25(3), 384–386;
Published: 10 June 2004

Primitive neuroectodermal tumors (PNETs) of the uterus are very rare. The histogenesis of these tumors is still unknown and the differential diagnosis includes a wide variety of tumor entities. We describe a rare case of a 68-year-old female who presented with persistent vaginal bleeding. Physical examination and CT-scan revealed a large tumor in the uterus. Macroscopically the tumor involved the uterine isthmus. Histological and immunohistochemical examination showed that the tumor fulfilled the diagnostic cri­teria set for PNET. Only a very small number of cases of PNETs of the uterus have been reported in the literature, thus no defini­tive conclusions concerning the therapeutic management and prognosis have been ascertained.

Uterine isthmus
Primitive neuroectodermal tumor
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