IMR Press / EJGO / Volume 25 / Issue 2 / pii/2004153

European Journal of Gynaecological Oncology (EJGO) is published by IMR Press from Volume 40 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on as a courtesy and upon agreement with S.O.G.

Case Report

Hyperplastic mesothelial cells in pelvic and abdominal lymph node sinuses mimicking metastatic ovarian microinvasive serous borderline tumor

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1 Department of Pathology, Zeynep Kamil Maternity Hospital, Istanbul (Turkey)
2 Obstetrics and Gynecology, Zeynep Kamil Maternity Hospital, Istanbul (Turkey)
3 Department of Obstetrics and Gynecology, University of Michigan Ann Arbor, Ml (USA)
Eur. J. Gynaecol. Oncol. 2004, 25(2), 236–238;
Published: 10 April 2004

Hyperplastic mesothelial cells within pelvic and abdominal lymph nodes were encountered in the staging procedure of a 32-year-old woman with a left ovarian microinvasive serous borderline tumor. Mesothelial hyperplasia was noted in the pelvic and abdominal peri­toneum. Intranodal mesothelial cells occupied the subcapsular sinus with subadjacent interfollicular sinuses involved less strikingly. These mesothelial cells were originally misdiagnosed as a metastatic serous borderline tumor. Histologic review and immunohisto­chemistry confirmed mesothelial origin. This case represents the second reported example of mesothelial cells within the lymph nodes of patients with ovarian serous tumors. Similar involvement of the mediastinal, cervical and internal mammary lymph nodes has been described in several patients with pleural effusions without neoplastic cells. lntranodal mesothelial cells should be distinguished from metastasis - an error ending in upper staging of a case.

Lymph node
Serous borderline tumor
Mesothelial hyperplasia
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