IMR Press / EJGO / Volume 24 / Issue 6 / pii/2003236

European Journal of Gynaecological Oncology (EJGO) is published by IMR Press from Volume 40 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with S.O.G.

Case Report

Malignant ovarian germ cell tumors: Analysis of 32 cases

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1 Department of Pathology, Medical Faculty of Dicle University, Diyarbakir, Turkey
2 Department of Obstetrics and Gynecology, Medical Faculty of Dicle University, Diyarbakir, Turkey
Eur. J. Gynaecol. Oncol. 2003, 24(6), 569–573;
Published: 10 December 2003
Abstract

Objective: In this study, some clinicopathologic characteristics and the outcome of patients with malignant ovarian germ cell tumors (MOGCT) were evaluated. Materials and Methods: The clinical charts and pathologic reports of 32 patients with MOGCT treated at the Department of Obstetrics and Gynecology, and diagnosed at the Department of Pathology, Medical Faculty of Dicle University, Turkey from 1983 to 1999 were reviewed. Results: Thirteen patients (40.6%) had dysgerminoma, nine (28. l %) had immature teratoma (four grade I, three grade 2, and two grade 3), eight (25%) had endodermal sinus tumor, and two (6.3%) patients had mixed germ cell tumors. Site of involvement was unilateral in 30 (l 9 on the right and 11 on the left) and bilateral in two. All patients underwent primary surgery and 26 patients combination chemotherapy. There seemed to be a relationship between pathologic findings and clinical outcome, and MOGCT histologic types may affect the prognosis. Conclusion: Dysgerminoma had a better prognosis than the nondysgerminomatous group (p < 0.05). This study provides additional data in confirmation of previous reports that management of MOGCT with fertility preservation is safe.

Keywords
Malignant ovarian germ cell tumors
Chemotherapy
Treatment
Fertility
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