IMR Press / EJGO / Volume 23 / Issue 6 / pii/2002239

European Journal of Gynaecological Oncology (EJGO) is published by IMR Press from Volume 40 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on as a courtesy and upon agreement with S.O.G.

Case Report

Primary small-cell carcinoma of the endometrium: Clinicopathological study of a case and review of the literature

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1 Department of Obstetrics and Gynaecology, “G. Chatzikosta” - General State Hospital, Ioannina (Greece)
2 Department of Pathology, “G. Chatzikosta” - General State Hospital, Ioannina (Greece)
Eur. J. Gynaecol. Oncol. 2002, 23(6), 577–581;
Published: 10 December 2002

Background: Small-cell carcinomas are almost always primary in the lungs and are highly malignant. These tumors may also occur in the female genital tract. However, primary small-cell carcinoma of the endometrium is extremely rare with very few cases reported in the English literature. This tumor may exhibit evidence of neuroendocrine differentiation and has a high propensity for systemic spread and poor prognosis. Case: A 55-year-old postmenopausal woman with primary small-cell carcinoma of the endometrium, FIGO stage Ib, underwent total abdominal hysterectomy with bilateral salpingo-oophorectomy and sampling node biopsies of the parametrial spaces, followed by adjuvant combined chemotherapy. Conclusion: A case of small-cell carcinoma of the endometrium, is reported and its clinical, histological and immunohistoche­mical features are discussed.

Small cell
Endometrial neoplasms
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