IMR Press / EJGO / Volume 23 / Issue 6 / pii/2002220

European Journal of Gynaecological Oncology (EJGO) is published by IMR Press from Volume 40 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with S.O.G.

Original Research

Chlamydia trachomatis infection in women with CIN and invasive uterine cervix cancer. Significance of hormonal status

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1 Chair of Oncology, K. Marcinkowski University School of Medicine, Poznan (Poland)
2 Departments of Gynecology and Obstetrics, Holy Family Clinic, K. Marcinkowski University School of Medicine, Poznan (Poland)
3 Chair of Radiology and Biology Faculty of Medicine, K. Marcinkowski University School of Medicine,  Poznan (Poland)
Eur. J. Gynaecol. Oncol. 2002, 23(6), 511–513;
Published: 10 December 2002
Abstract

In women with CIN at fertile age and those over 50 years of age, EGFR expression is lower in the presence of Chlamydia tra­chomatis (Cht) infection. In all Cht infected women over 50 years of age expression of Ki 67 is higher; the increase is significant among women with inva­sive carcinoma. In these groups of women with CIN and invasive carcinoma TGF-α expression is insignificantly augmented. Chronic Cht infection is associated with cervical hypertrophy.

Keywords
Cht infection
CIN
Cervical cancer
Hormonal status
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