IMR Press / EJGO / Volume 23 / Issue 3 / pii/2002155

European Journal of Gynaecological Oncology (EJGO) is published by IMR Press from Volume 40 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on as a courtesy and upon agreement with S.O.G.

Original Research

The significance of local cellular immune response of women 50 years of age and younger with endometrial carcinoma

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1 Department of Pathology, Osmanga?i University Faculty of Medicine, Eskisehir (Turkey)
2 Department of Obstetrics and Gynecology, Gynecologic Oncology Unit, Osmanga?i University Faculty of Medicine, Eskisehir (Turkey)
3 Department of Biostatistics, Osmanga?i University Faculty of Medicine, Eskisehir (Turkey)
Eur. J. Gynaecol. Oncol. 2002, 23(3), 243–246;
Published: 10 June 2002

Objective: Local cellular immune response and traditional histopathologic parameters in endometrial carcinoma patients 50 years old and younger were compared with those of patients older than 50 years of age. Materials and Methods: We retrospectively compared the clinicopathologic factors and outcomes of 24 younger and 82 older women who were operated on for endometrioid type endometrial carcinoma at our institution. Results: No significant difference was determined in survival with respect to age and menopausal status in patients with endo­metrial carcinoma. Younger and older age groups had a similar distribution of most pathologic features including myometrial inva­sion, cervical involvement, lymph node metastasis, vascular invasion, perivascular lymphocytic infiltrates and tumor infiltrating lymphocytes. While older women had higher-grade tumors, younger women had more frequent ovarian metastasis. Tumor infilra­ting lymphocytes were seen more frequently in the postmenopausal group than those of the premenopausal group. Conclusion: The distribution of local cellular immune response, most histopathologic parameters and survival were the same for younger and older women.

Endometrial carcinoma
Menopausal status
Local cellular immune response
Traditional histopathologic para-meters.
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