IMR Press / EJGO / Volume 22 / Issue 5 / pii/2001181

European Journal of Gynaecological Oncology (EJGO) is published by IMR Press from Volume 40 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on as a courtesy and upon agreement with S.O.G.

Case Report

Extragonadal retroperitoneal endodermal sinus tumor in an eight-month-old female infant

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1 Department of Radiology, Democritus University of Thrace, Alexandroupolis, Greece
2 Department of Pathology, Democritus University of Thrace, Alexandroupolis, Greece
Eur. J. Gynaecol. Oncol. 2001, 22(5), 345–346;
Published: 10 October 2001

We describe a rare case of an extragonadal retroperitoneal endodermal sinus (yolk sac) tumor in the minor pelvis. Radiologic investigation, which included abdominal ultrasound and computed tomography (CT), showed a large soft tissue mass occupying the pelvic cavity. Radionuclide bone scans demonstrated bone metastases. The serum alpha fetoprotein was elevated. Pathologic exa­mination of the surgical specimen revealed extragonadal yolk sac tumor. Immunohistochemically, the tumor was positive for a-feto­protein and cytokeratins. After postoperative combination therapy, follow-up CT showed decreasing tumoral disease, while serum alpha fetoprotein returned to normal.

Endodermal sinus tumor
Yolk sac tumor
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