IMR Press / EJGO / Volume 22 / Issue 1 / pii/2001104

European Journal of Gynaecological Oncology (EJGO) is published by IMR Press from Volume 40 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on as a courtesy and upon agreement with S.O.G.

Original Research

Primary vaginal melanoma and long-term survivorsa

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1 Northern Gynecological Oncology Centre, Queen Elizabeth Hospital, Gateshead, UK
2 Division of Gynecologic Oncology, Antwerp University Hospital, Antwerp, Belgium

aPresented at the XVI FIGO World Congress, Washington, D.C. (USA) 3-8 September, 2000

Eur. J. Gynaecol. Oncol. 2001, 22(1), 20–22;
Published: 10 February 2001

Vaginal melanoma is a rare and highly malignant disease. This report describes the characteristics and clinical course of all patients treated at one institute (Northern Gynaecological Oncology Centre, UK) over the last 25 years. Of a total of nine patients identified with a primary malignant vaginal melanoma, only one patient survived for more than five years. A literature review reveal­ed only 21 reported cases with a survival greater than five years. The most important factor for survival appears to be the tumour size. Treatment modality varied equally within the group of long-term survivors (27% radical surgcry, 27% wide local excision, 27% radiotherapy, 14% wide local excision and radiotherapy, and 5% unknown therapy). The prognosis of patients with primary malignant melanoma is poor, regardless of primary therapy (conservative or radical). Conservative treatment and accurate investi­gation of every discoloured lesion is recommended.

Vaginal melanoma
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