IMR Press / EJGO / Volume 21 / Issue 5 / pii/2000223

European Journal of Gynaecological Oncology (EJGO) is published by IMR Press from Volume 40 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on as a courtesy and upon agreement with S.O.G.

Original Research

Complications following combined surgery (radical vulvectomy versus wide local excision) and radiotherapy for the treatment of carcinoma of the vulva: Report of 73 patients

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1 Assoc. Professor, University of Gaziantep, Sahirbay Medical Center, Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, Gazianep, Turkey
2 Professor, University of Texas M.D. Anderson Cancer Center, Department of Gynecologic Oncology, Houston, USA
3 Professor, University of Texas M.D. Anderson Cancer Center, Department of Radiotherapy, Houston, Texas, USA
Eur. J. Gynaecol. Oncol. 2000, 21(5), 501–503;
Published: 10 October 2000

Cancer of the vulva is uncommon, accounting for only 5% of all gynecologic malignancies, and usually occurs in women over 60 years of age. The historic treatment of choice for invasive squamous cell carcinoma of the vulva is radical vulvectomy with bila­teral inguinal lymphadenectomy, which has produced excellent long-term survival. We retrospectively analyzed the complications of wide local excision plus postoperative radiotherapy compared with those of radical vulvectomy and bilateral lymphadenectomy plus pre-or postoperative radiotherapy in 73 patients with vulvar cancer. There were no significant differences among these treatments in terms of primary tumor control, 5-year disease-free survival, and overall survival. Based on these results, the best treatment alternative for advanced vulvar cancer is wide local excision plus radiotherapy, as this method retains the high survival of traditional therapy but has less morbidity.

Radical vulvectomy
Wide local excision
Vulvar cancer
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