IMR Press / EJGO / Volume 21 / Issue 4 / pii/2000196

European Journal of Gynaecological Oncology (EJGO) is published by IMR Press from Volume 40 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on as a courtesy and upon agreement with S.O.G.

Case Report

Surgical treatment of invasive carcinoma of the vulva. Our experience

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1 Department of Experimental Medicine, Division of Obstetrics and Gynecology, University of L’Aquila, Italy
Eur. J. Gynaecol. Oncol. 2000, 21(4), 393–395;
Published: 10 August 2000

Objective. The purpose of this study was to investigate the clinical findings, treatment and outcome of patients with vulvar car­cinoma in the L’Aquila area. Methods. Fifteen cases of vulvar carcinoma seen between September 199 I and December 1999 at the Department of Obstetrics and Gynecology of the University of L’Aquila were reviewed. Clinical, pathologic, surgical and follow-up data were collected from patient records. Mean age at diagnosis was 66.4 years. All patients were evaluated through a careful medical history and physical examination, vulvoscopy, abdomino-pelvic CT or MR, urethrocystoscopy, rectocolonscopy and SCC, and CEA determination. Radical surgery included six patients treated by the Taussig-Way operation. Modified radical surgery accounted for nine patients treated by the Byron three-incision approach. Results. The major early complication was groin wound breakdown which occurred in four cases. The major late complication was chronic leg edema which was reported in six patients. The average number of nodes removed per patient was 19.5. Seven patients (46.7%) had a T2N0M0 pathologic stage, four (26.7%) were T2NlM0, four (26.7%) TlN0M0. Five patients died of local and distant recurrences within 37 months after surgical treatment; ten patients are alive, nine are apparently free from disease whereas one presented local and systemic recurrence within 18 months after surgery. Conclusions. Vulvar carcinoma predominantly affects older women. Most patients in our series (11/15) had tumors more than 2 cm in diameter. Although the vulva is an external organ and early detection should be achieved, many patients presented with exten­sive primary lesions due to both patient and physician delay. Stage of disease, tumor size, and nodal metastases are potential pro­gnostic factors useful in selecting patients for a more conservative surgical approach.

Vulvar cancer
Prognostic factors
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