IMR Press / EJGO / Volume 21 / Issue 4 / pii/2000194

European Journal of Gynaecological Oncology (EJGO) is published by IMR Press from Volume 40 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on as a courtesy and upon agreement with S.O.G.

Case Report

Mullerian adenosarcoma of the uterus: Case report and review of literature

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1 Unit of Gynecologic Oncology, Department of Obstetrics and Gynecology, Ben-Gurion University of the Negev, Beer-Sheva, Israel
2 Institute of Pathology, Soroka Medical Center and Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel
Eur. J. Gynaecol. Oncol. 2000, 21(4), 387–390;
Published: 10 August 2000

Mullerian adenosarcoma – a variant of mullerian mixed mesodermal tumor of the uterus - is typically composed of benign but sometimes mildly atypical glandular epithelial elements admixed with malignant sarcomatous stroma. This rare tumor, which accounts for only about 8% of all uterine sarcomas, usually originates in the endometrium and grows as a polypoid mass within the endometrial cavity. The most prevailing presenting symptom is abnormal vaginal bleeding and the most common finding is a poly­poid mass protruding through a dilated cervical canal. The case of a woman, who at age 62 presented with symptoms and signs of acute pelvic inflammatory disease and on vaginal examination an infected mullerian adenosarcoma protruding through a dilated cer­vical canal was discovered, is reported. Treatment consisted of extensive antibiotic treatment and surgery comprised of total abdo­minal hysterectomy and bilateral salpingo-oophorectomy followed by postoperative adjuvant pelvic radiotherapy. One year later, the patient is alive with no evidence of disease.

Mullerian mixed mesodermal tumor: Uterine sarcoma
Uterine corpus
Vaginal bleeding
Total abdominal hysterectomy
Pelvic radiotherapy
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