IMR Press / EJGO / Volume 20 / Issue 5-6 / pii/1999210

European Journal of Gynaecological Oncology (EJGO) is published by IMR Press from Volume 40 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on as a courtesy and upon agreement with S.O.G.

Case Report

Uterine metastases from breast cancer in a patient under tamoxif en therapy

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1 Department of Pharmacology, Gynaecology and Obstetrics, University of Sassari, Italy
2 Department of Radiology, University of Sassari, Italy
3 Department of Pathology, University of Sassari, Italy
Eur. J. Gynaecol. Oncol. 1999, 20(5-6), 416–417;
Published: 10 October 1999

The authors report a case of metastases of breast cancer confined to the uterus and cervical subserous leiomyoma in a post­menopausal woman under tamoxifen therapy for two years. After abnormal uterine bleeding, pathologic examination on biopsy of a cervical polyp revealed cervical involvement secondary to lobular breast cancer. The patient underwent total abdominal hysterec­tomy with bilateral salpingo-oophorectomy. Pathologic examination of the surgical specimen revealed both invasion of breast origin and of the cervix until the isthmus, endometrium and cervical subserous leiomyoma. The adnexa uteri were not affected. The pos­sibility of uterine metastases in patients suffering from breast cancer, either undergoing tamoxifen therapy or not, always has to be considered.

Breast cancer
Uterine metastases
Tamoxifen therapy
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