IMR Press / EJGO / Volume 20 / Issue 5-6 / pii/1999209

European Journal of Gynaecological Oncology (EJGO) is published by IMR Press from Volume 40 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on as a courtesy and upon agreement with S.O.G.

Original Research

Carcinoma of cervix, the King Faisal Specialist Hospital & Research Center Experience - The need for screening for cervical cancer in developing countries

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1 Section of Radiation Oncology, Department of Oncology, Kingdom of Saudi Arabia
2 Section of Gynecologic Oncology, Department of Obstetrics and Gynecology, Kingdom of Saudi Arabia
3 Department of Oncology, Kingdom of Saudi Arabia
4 Oncology Data Unit King Faisal Specialist Hospital & Research Center, Riyadh, Kingdom of Saudi Arabia
Eur. J. Gynaecol. Oncol. 1999, 20(5-6), 412–415;
Published: 10 October 1999

The King Faisal Specialist Hospital and Research Center opened in 1975 to provide specialized medical treatment to the citizens of Saudi Arabia and to promote prevention of disease through research and education. It is a national and middle eastern tertiary care hospital for oncology and a principle center for radiation therapy in Saudi Arabia. In this retrospective study, 504 patients with carcinoma of the cervix were analysed. Of the 504 patients, 410 received treatment with curative intent, which comprised radical surgery alone, radical radiation alone or combination surgery and radiation. The overall 3, 5 and 10 years survival of all 504 patients was 64%, 55% and 40%, respectively and for 410 patients treated with curative intent it was 74%, 61 % and 51 %, respectively. Multivariate analysis, using the Cox regression method, showed that the stage of the disease is the only significant prognostic factor influencing relapse-free survival. Stage for stage, treatment outcomes at King Faisal Specialist Hospital and Research Center match those achieved in the First world, but two-thirds of patients (rather than one-third) present with advanced disease at diagnosis. Therefore, any improvement in overall outcomes will require earlier diagnosis, achievable only through an effective screening program in the Kingdom of Saudi Arabia and similarly in the other Third world countries where patients present with advanced stage disease.

Carcinoma of cervix
Screening program in developing countries
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