IMR Press / EJGO / Volume 20 / Issue 5-6 / pii/1999207

European Journal of Gynaecological Oncology (EJGO) is published by IMR Press from Volume 40 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on as a courtesy and upon agreement with S.O.G.

Original Research

Prognostic factors and selective use of vaginal hysterectomy in early stage endometrial carcinoma

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1 Department of Obstetrics and Gynaecology, University of Bari, Italy
Eur. J. Gynaecol. Oncol. 1999, 20(5-6), 408–411;
Published: 10 October 1999

Introduction. Endometrial cancer represents the fourth most frequent malignancy in women of any age, tending to become the most common gynaecological tumor in developed Countries. A retrospective analysis has been conducted on the prognostic factors of endometrial neoplasm during 15-years experience (1977-1991). Material and Methods. 321 patients affected by stage I and II endometrial carcinoma have been treated surgically first hand. Sur­gical-pathological staging and prognostic factors were reviewed and related to follow-up and 5-year survival rate. Results. The age-peak of patients was 50-70 years; prevalent histologic type was adenocarcinoma (95.6%); 269 patients were in stage I and 52 in stage II. In stage I disease overall 5-year survival rate resulted to be 81.4%, while in stage II it fell to 59.6%. Discussion. Myometrial involvement by adenocarcinomatous cells is probably the most important prognostic factor, considenng its reliability and non-contradictory evaluation. Our data confirm there is no difference in impact on 5-year survival between abdominal and vaginal routes in clinical stage I and occult stage II endometrial carcinoma.

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