IMR Press / EJGO / Volume 20 / Issue 5-6 / pii/1999202

European Journal of Gynaecological Oncology (EJGO) is published by IMR Press from Volume 40 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on as a courtesy and upon agreement with S.O.G.

Original Research

Immunohistochemical expression of BerEP4, a new epithelial antigen, in endometrial carcinoma: correlation with clinical parameters

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1 Department of Pharmacology, Gynaecology and Obstetrics, Italy
2 Institute of Pathology, University of Sassari, Italy
Eur. J. Gynaecol. Oncol. 1999, 20(5-6), 393–395;
Published: 10 October 1999

Objective: To assess the immunochemical expression of BerEP4, a new epithelial antigen in endometrial carcinoma. Methods: We studied 45 cases of endometrial carcinoma in which the BerEP4, CEA and TAG-72 antigens were searched by an immunohistochemical method. We evaluated the correlations among the immunohistochemical positivity and the grading, histotype, stage and receptorial status of the neoplasia. Results: CEA was positive in 29 out of 45 cases (64.4%), TAG-72 in 17 out of 45 cases (37.7%) and BerEP4 in 31 out of 45 cases (68.9%). Both TAG-72 and CEA were inversely related to the grading while, with regard to the histotype, CEA resulted as highly positive in the 5 cases of adenoacanthoma. Conclusion: BerEP4 did not show any correlation with grading, histotype, stage of disease or receptorial status of the carcinoma.

Endometrial carcinoma
BerEP4 antigen
CEA antigen
TAG-72 antigen
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