IMR Press / EJGO / Volume 20 / Issue 2 / pii/1999136

European Journal of Gynaecological Oncology (EJGO) is published by IMR Press from Volume 40 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on as a courtesy and upon agreement with S.O.G.

Original Research

Prognostic factors in stage IB-IIA cervical carcinomas treated with postoperative radiotherapy

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1 Ankara University Medical School, Department of Radiation Oncology, Dikimevi, Ankara, Turkey
2 SSK Maternity Hospital, Department of Gynecologic Oncolog,Etlik, Ankara, Turkey
Eur. J. Gynaecol. Oncol. 1999, 20(2), 131–135;
Published: 10 April 1999

Purpose: This study investigated the prognostic significance of age, stage, tumor size, pelvic lymph node metastasis (PLM), surgical margin invasion, overall radiotherapy time (ORT), and interval between radiotherapy and surgery (IRS) in stage IB-IIA cervical carcinoma. Method and Materials: 100 patients treated with radical hysterectomy and postoperative radiotherapy were evaluated retrospec­tively. Results: The 5-yr overall survival (OS), disease-free survival (DFS), and pelvic control rate (PC) were 83.6%, 82.8%, and 91.8%, respectively. PLM (p = 0.008), IRS (p = 0.01), ORT (p = 0.007), and tumor size (p = 0.028) were found to be significant on PC. PLM (p = 0.04), ORT (p = 0.04), and IRS (p = 0.01) were significant on OS. PLM was significant (p = 0.04) and IRS was marginally significant (p = 0.06) on DFS. After multivariate analysis, PLM was significant on OS, DFS and PC. Recurrences were seen in 14 patients. Conclusion: According to this study PLM, IRS, and ORT are the most important prognostic factors. Recurrences outside the radiation volume leads to treatment failure.

Cervical carcinoma
Prognostic factors
Interval surgery-radiation
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