IMR Press / EJGO / Volume 18 / Issue 1 / pii/1997114

European Journal of Gynaecological Oncology (EJGO) is published by IMR Press from Volume 40 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on as a courtesy and upon agreement with S.O.G.

Original Research

Validity of colposcopy to identify and grade squamous intraepithelial lesions among venezuelan women

Show Less
1 Servicio de Medicina Oncológica , Central de Venezuela, Caracas, Venezuela
2 Servicio de Ginecología Oncológica, Instituto Oncológico Luis Razetti, Universidad, Central de Venezuela, Caracas, Venezuela
3 Hospital Miguel Pérez Carre?o, Caracas, Venezuela
4 Servicio de Medicina 2, Hospital Vargas de Caracas, Universidad Central de Venezuela, Caracas, Venezuela
Eur. J. Gynaecol. Oncol. 1997, 18(1), 57–60;
Published: 10 February 1997

To assess the validity of colposcopy to correctly detect and grade squamous intraepithelial lesions (SIL) in Venezuelan women, we did a prospective, nonrandomized and cross sectional study on patients referred with low-grade and high-grade SIL. After a second cervical smear, they were colposcopically evaluated and biopsied. The outcome measures were interobserver variation, sen­sitivity, specificity, and predictive values. Ninety-nine patients were evaluable. Colposcopy had poor agreement with repeat cervi­cal smears, and moderate to good agreement with conization biopsy (kappa = 0.55; 95% C.I.: 0.45 to 0.65), with a sensitivity of 0.87, a spec1ficity of 0.69, a positive predictive value of 0.85 and a negative predictive value of 0.7l for high-grade SIL The cri­terion of colposcopic vascular atypias was accurate enough to detect and grade SIL, showing good agreement with histopathology. Because of the disparity of results in previous reports, only a carefully designed, randomized study will settle this question.

Cervical intraepithelial neoplasia
Observer variation
Sensitivity and specificity
Back to top