IMR Press / CEOG / Special Issues / methods_approaches_gynecology_obstetrics

Promising Rare and Uncommon Methods and Approaches in Gynecology and Obstetrics

Submission deadline: 30 September 2022
Special Issue Editors
  • Anna Birková, PhD
    Department of Medical and Clinical Biochemistry, Pavol Jozef Šafárik University in Košice, Faculty of Medicine, Košice, Slovakia
    Interests: Gynecological cancer; Biochemistry; Metabolism; Oxidative stress; Public health; Biomarkers; The role of obesity-related molecules in womens cancer (adipokines, lipoprotein subfractions)
  • Vladimír Kraus Jr., MD, PhD
    Department of gynaecology and Obstetrics, Pavol Jozef Šafárik University in Košice, Faculty of Medicine, Košice, Slovakia; Department of gynaecology and Obstetrics, Louis Pasteur University Hospital, Košice, Slovakia
    Interests: miniinvasive surgery; premature birth; cancer screening algorithms
  • Katarína Dubayová, PhD
    Department of Medical and Clinical Biochemistry, Pavol Jozef Šafárik University in Košice, Faculty of Medicine, Košice, Slovakia
    Interests: molecular genetics; biochemistry; cancer; fluorescence
Special Issue Information

Dear Colleagues,

With the increased understanding concerning the etiology and pathophysiology of diseases, the era of generalized medicine based on evidence has been upgraded to a personalized approach to the patient. Many robust methods have come to the fore, based upon which it is now possible to specify targeted and valuable markers for routine diagnosis, prognosis, or targeted treatment. These may include a wide range of diagnostic and therapeutic procedures or various smart tools for interpreting data based on artificial intelligence.

The recent decade has witnessed a rise in the use of cell-free DNA, both in prenatal testing as well as in diagnostics in gynecological cancers. When mentioning genetics, we cannot ignore CRISPR. Notwithstanding the ethical issues, the possibilities of embryonic genome editing offer new tools for cancer research and even treatment. Early cancer diagnostics will unfortunately always be a central topic, and the enamoration with mRNA is slowly yielding practical results. Moreover, the search for the next (hopefully specific enough) novel serum biomarker will never cease.

HPV vaccination has led to a significant decrease in cervical cancer incidence in countries with a functional vaccination program. It has also contributed to a paradigm shift in cervical cancer screening, where the classical Pap smear is being replaced with serial HPV testing for persistent infection, as per ACOG recommendations updated in April, 2021.

The COVID-19 disease, of course, has affected almost every aspect of our everyday life. For pregnant women, it has also presented an elevated risk of preterm or even stillbirth. Vaccination propagates slower than desired due to the extraordinary information divide and uncertainty. Furthermore, vaccination can lead to short-term disruption of the menstrual cycle for menstruating women.

Even something as classical as the C-section is being challenged with new ideas. Vaginal seeding, or the transfer of vaginal flora onto a newborn infant, is being discussed. A growing number of patients also request incorporating a more family-oriented and friendly approach with various aspects of unmedicated vaginal birth, in what is being called a gentle C-section. The obstetric community is also anticipating new ways to handle difficult operative vaginal births, with the upcoming certification of the ODON device.

This Special Issue is devoted to a wide range of hitherto non-routine methods that have the potential to contribute to a more targeted diagnosis or treatment of a wide range of gynecological and obstetric practices, from oncology to reproductive medicine.

Dr. Anna Birková

Guest Editor

personalized medicine
experimental methods
novel biomarkers
cell-free DNA
vaginal seeding
gentle C-section
Manuscript Submission Information

Manuscripts should be submitted via our online editorial system at by registering and logging in to this website. Once you are registered, click here to start your submission. Manuscripts can be submitted now or up until the deadline. All papers will go through peer-review process. Accepted papers will be published in the journal (as soon as accepted) and meanwhile listed together on the special issue website. Research articles, reviews as well as short communications are preferred. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office to announce on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts will be thoroughly refereed through a double-blind peer-review process. Please visit the Instruction for Authors page before submitting a manuscript. The Article Processing Charge (APC) in this open access journal is 1500 USD. Submitted manuscripts should be well formatted in good English.

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