IMR Press / CEOG / Special Issues / adenomyosis_fertility

Adenomyosis in Women Wishing to Conceive: Fertility and Obstetric Outcomes

Submission deadline: 15 May 2023
Special Issue Editor
  • Laura Buggio, MD
    Gynecology Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy
    Interests: endometriosis; adenomyosis; uterine fibroids; gynecology; contraception
Special Issue Information

Dear Colleagues,

Until recently, adenomyosis was usually diagnosed following a hysterectomy by histologic examination. Therefore, there was minimal interest in this disorder's effect on fertility and pregnancy outcomes since the diagnosis could not be made prior to the pregnancy. However, since it is now fairly easy to make a diagnosis of adenomyosis using imaging techniques (ultrasonography and MRI), the interest in the potentially negative impact of adenomyosis on fertility and pregnancy outcomes has been increased.

Several mechanisms have been proposed to explain the potential negative effect of adenomyosis on fertility and implantation, such as impairment of the uterine system to sperm transport secondary to the alteration of the normal myometrial structure and presence of uterine dysperistalsis which may limit the probability of embryo implantation. In addition, the presence of abnormally high levels of free radicals in the uterus could create an unfavorable environment for embryo development and implantation.

In this Special Issue on adenomyosis, our aim is to provide additional studies and reviews, investigating the potential impact of this disease on fertility and obstetrical outcomes.

Dr. Laura Buggio

Guest Editor

obstetric outcome
Manuscript Submission Information

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