IMR Press / CEOG / Special Issues / 1585734544213

 Inflammation during embryonic development - Studying the consequences of chorioamnionitis

Section: Embryology
Submission deadline: 01 October 2020
Special Issue Editors
Nikolaos Papadopoulos, MD, PhD
Democritus University of Thrace Dragana, University Hospital of Alexandroupolis, Medical School, Alexandroupolis, 68132, Evros, Greece
Interests: Pediatrics; Pediatric rhinitis
Special Issue Information

Dear Colleagues,

Inflammation during embryonic development from highly virulent organisms constitutes a serious complication of pregnancy with a high rate of fetal morbidity and mortality. This condition is due mostly from microoranisms such as, E. coli, group B streptococci and anaerobic bacteria that are normally present in the vagina. These pathogenic microorganisms ascend into the uterine cavity affecting at first the membranes that surround the fetus (chorion and amnion), a condition called acute chorioamnionitis. Clinically, the chorioamnionitis is characterized by maternal fever, leukocytosis, tachycardia, uterine tenderness and finally causing an inflammatory cascade that leads to preterm rupture of membranes / preterm birth.

Evidence from humans and experimental models has been shown that chorioamnionitis is associated with a fetal inflammatory response which is characterized by increased release of systemic inflammatory cytokine and toxic molecules. It seems that these substances induce secondary growth disorders on fetal development which have been associated with the occurrence of serious complications and congenital malformations in various organs of the fetus. Disturbances that have been recorded in the development of the brain, sensory organs of sight and hearing, in the respiratory, gastrointestinal and urinary tract, and finally disorders of embryonic hematopoiesis in the liver, spleen and thymus gland.

Prof. Papadopoulos Nikolas

Guest Editor

Keywords
Fetal development
Chorioamnionitis
Consequences
Manuscript Submission Information

Manuscripts should be submitted via our online editorial system at https://imr.propub.com by registering and logging in to this website. Once you are registered, click here to start your submission. Manuscripts can be submitted now or up until the deadline. All papers will go through peer-review process. Accepted papers will be published in the journal (as soon as accepted) and meanwhile listed together on the special issue website. Research articles, reviews as well as short communications are preferred. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office to announce on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts will be thoroughly refereed through a double-blind peer-review process. Please visit the Instruction for Authors page before submitting a manuscript. The Article Processing Charge (APC) in this open access journal is 1500 USD. Submitted manuscripts should be well formatted in good English.

Published Paper (1 Paper)
21
Download
1
Citations
104
Views
Back to top