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Clinical and Experimental Obstetrics & Gynecology (CEOG) is published by IMR Press from Volume 47 Issue 1 (2020). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with S.O.G.
Original Research
Use of B.C.G. as loco-regional aspecific immunostimulator in cervical carcinoma
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1
Department of Obstetrics and Gynecology, Hospital of Schio (Vicenza, Italy)
2
“Centro Tumori” Hospital of Vicenza (Italy)
3
Institute of Pathologic Anatomy, Hospital of Vicenza (Italy)
Clin. Exp. Obstet. Gynecol. 1982, 9(3), 186–188;
Published: 10 September 1982
Abstract
This study concerns the possible use of BCG in oncologic gynecology for loco regional stimulation or loco aspecific active immunotherapy. The Authors administered BCG into the portio of 45 women affected by cervical cancer (stage I and stage II) immediately after the cytohistologic diagnosis and 21 days before the surgical intervention. The Authors conclude that the submucosal inoculation of BCG into the portio causes hyperplastic reactions in this area and in the locoregional lymphatic system with stimulation of the T-lymphocytes and with production of Interferon. Anyway this stimulation has a limited duration.