IMR Press / CEOG / Volume 7 / Issue 2 / pii/1634266336859-1199984504

Clinical and Experimental Obstetrics & Gynecology (CEOG) is published by IMR Press from Volume 47 Issue 1 (2020). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with S.O.G.

Original Research
Serum levels of benzydamine following the topical use of this drug in gynecology
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1 1st Gynecological and Obstetric Clinic, University of Pisa
2 F. Angelini Research Institute, Rome
Clin. Exp. Obstet. Gynecol. 1980, 7(2), 84–88;
Published: 10 June 1980
Abstract

The serum levels of benzydamine were studied after administration by vaginal douching (at a concentration of 0.0%) to patients with and without vaginal inflammation. In both experimental groups benzydamine produced similar serum concentrations which were lower than those obtained by other administration routes, excluding the possibillity of eventual systemic effects. These data are a further confirmation that, whenever possible, topical use is preferable to systemic use in order to reduce the incidence of systemic side effects to a minimum and to obtain a more selective therapy.
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