IMR Press / CEOG / Volume 6 / Issue 4 / pii/1634267387419-1156463851

Clinical and Experimental Obstetrics & Gynecology (CEOG) is published by IMR Press from Volume 46 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on as a courtesy and upon agreement with S.O.G.

Open Access Original Research
Prostaglandin E2-induced inhibiting effect on human plasma prolactin in early puerperium
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1 Dcpartment of Obstetrics and Gynecology, University of Cagliari
Clin. Exp. Obstet. Gynecol. 1979, 6(4), 276–279;
Published: 10 December 1979

On the fourth day after delivery PGE2 was given orally in a dose schedule of 2 mg every 30 minutes for a total dose of 8 mg to twelve puerperal women. Serum prolactin. Showed a significant decrease in comparison to basal levels and to those of controls during the control times. The authors suggest that PGE2-induced prolactin decrease could be mediated by hypothalamic dopaminergic neurons or by an hypothetic prostaglandin-receptor in the brain.
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