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Clinical and Experimental Obstetrics & Gynecology (CEOG) is published by IMR Press from Volume 47 Issue 1 (2020). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with S.O.G.
Original Research
Correlation between glucagon, insulin and glycaemia after oral loading with glucose at various stages of pregnancy
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1
Obstetric Gynaecological Clinic, University of L’Aquila
Clin. Exp. Obstet. Gynecol. 1979, 6(3), 189–191;
Published: 10 September 1979
Abstract
The Authors studied the progress of glycaemia, insulinaemia and glucagonaemia after oral loading of 100 g of glucose in a group of women at different ages of pregnancy (30th-40th week). Their results demonstrate with regard to the glycaemic curve, a slowing to the initial glycaemic values. This then tended to return at least partially to normal during the last weeks of pregnancy. As regards insulin the Authors noted a gradual increase of its secretion as pregnancy progressed. In the case of glucagon there was inhibition of the alpha cells, expressed as hypoglucagonaemia; the hyperglucagonaemia observed 30 min. after oral loading with glucose might be interpreted as direct stimulation of the alpha cells by cholecystokinin.