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Clinical and Experimental Obstetrics & Gynecology (CEOG) is published by IMR Press from Volume 47 Issue 1 (2020). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with S.O.G.
Original Research
Diagnosis and treatment of patients who have become sterile due to prolactin-secreting pituitary aden oma
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1
II Obstetric and Gynaecological Clinic, University of Rome
2
I Obstetric and Gynaecological Clinic, University of Rome
3
Department of Obstetrics and Gynecology, Westfalische Wilhelms Universitat, Munster - Germany
Clin. Exp. Obstet. Gynecol. 1978, 5(3-4), 93–103;
Published: 10 September 1978
Abstract
The present study reports the endocrinological and radiological features of 10 hyperpro-lactinaemic patients with macro (4 patients) and microadenoma (6 patients) of the pituitary. A more affected hormonal situation seems to be present in patients where more pronoun-ced radiographic changes are found. In the light of this evidence it appears that polytomography of the sella is mandatory wherever a microadenoma of the pituitary has to be ruled out. CB-154 treatment appears to be mostly effective in the tratment of hyper-prolactinaemic patients, resulting within few months in resumption of menses and ovulation. The risk of pregnancy and the possible thera-peutic approaches to the problem are discussed.