Academic Editor: Michael H. Dahan
Background: Polycystic ovary syndrome (PCOS) is commonly associated
with insulin resistance (IR), hyperinsulinemia, and dyslipidemia, which play a
role in the development of endothelial dysfunction and promote the early onset of
cardiovascular diseases. The aim of this study was to evaluate
the clinical importance of pentraxin-3 levels in PCOS patients. Methods:
Forty-five female patients diagnosed with PCOS according to the 2003 Rotterdam
criteria and 42 healthy women were included in the study. All women studied were
tested within 3 and 5 days of their menstrual cycle. Ultrasonographic evaluation
of each patient was first conducted using the suprapubic method. Serum PTX-3,
endothelin 1 (ET-1), vascular cell adhesion molecule 1 (VCAM-1), intercellular
adhesion molecule 1 (ICAM-1), and nitric oxide levels were measured using the
enzyme-linked immunosorbent assay method. Results: Pentraxine-3 (PTX-3)
levels in the patient group were significantly lower than those in the control
group (p