IMR Press / CEOG / Volume 47 / Issue 5 / DOI: 10.31083/j.ceog.2020.05.2094
Open Access Case Report
Ovarian teratoma with anti-N-methyl-D-aspartate receptor encephalitis, a type of limbic encephalitis: a review of the literature and a case report in Korea
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1 Department of Obstetrics and Gynecology, Hallym University Kangdong Sacred Heart Hospital, Seoul, Republic of Korea
2 Department of Neurology, Hallym University Kangdong Sacred Heart Hospital, Seoul, Republic of Korea
3 Department of Laboratory Medicine, Konkuk University School of Medicine, Seoul, Republic of Korea

Contributed equally.

Clin. Exp. Obstet. Gynecol. 2020, 47(5), 774–780; https://doi.org/10.31083/j.ceog.2020.05.2094
Submitted: 26 March 2020 | Accepted: 12 May 2020 | Published: 15 October 2020
Abstract

Anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis is a type of limbic encephalitis that is resulted by an autoimmune processes; it is a rare autoimmune encephalitis caused by the NMDA receptor antibody secreted by all kinds of tumors. This paraneoplastic syndrome is frequently associated with ovarian teratomas; however, neural cells expressing anti-NMDAR may also be involved in the disease. We report a patient with a case of anti-NMDAR encephalitis associated with an ovarian teratoma, and present a literature review of 16 cases of anti-NMDAR encephalitis in Korean women.

Keywords
Anti-N-methyl-D-aspartate receptor encephalitis
Teratoma
Anti-NMDAR autoimmune encephalitis with teratoma
Encephalitis
Ovarian neoplasm
Figures
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