IMR Press / CEOG / Volume 47 / Issue 3 / DOI: 10.31083/j.ceog.2020.03.5215
Open Access Case Report
Recurrent hydatidiform mole: when to stop?
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1 Department of Obstetrics and Gynecology, Acibadem University School of Medicine, Istanbul, Turkey
2 Diagnostics Center for Genetic Diseases, University of Trakya, Trakya Medical Faculty, Edirne, Turkey
*Correspondence: (ESRA OZBASLI)
Clin. Exp. Obstet. Gynecol. 2020, 47(3), 424–426;
Submitted: 4 March 2019 | Accepted: 4 June 2019 | Published: 15 June 2020
Copyright: © 2020 Ozbasli et al. Published by IMR press.
This is an open access article under the CC BY 4.0 license

Recurrent hydatidiform mole (RHM) is defined as two or more repeated molar pregnancies in the same patient. Familial recurrent hydatidiform mole (FRHM) is a rare condition in which the patient has relatives with the same condition and mutations. Maternal mutations in the NLRP7 gene are mostly observed in RHM. The authors report a patient from Turkey with a history of seven molar pregnancies who had an aunt with similar obstetric history and NLRP7 mutations.

Familial hydatidiform mole
Ovum donation
Genomic imprinting
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