IMR Press / CEOG / Volume 46 / Issue 5 / DOI: 10.12891/ceog4936.2019

Clinical and Experimental Obstetrics & Gynecology (CEOG) is published by IMR Press from Volume 47 Issue 1 (2020). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on as a courtesy and upon agreement with S.O.G.

Open Access Review
Relationship between endometriosis and vitamin D status - a review
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1 Medical Center Angelius, Katowice, Bytom, Poland
2 Chair and Clinical Department of Gynecology, Obstetrics and Oncological Gynecology in Bytom, Bytom, Poland
*Correspondence: (M. PALIGA)
Clin. Exp. Obstet. Gynecol. 2019, 46(5), 674–678;
Published: 10 October 2019

The impact of vitamin D on multiple biological processes is nowadays widely accepted. Vitamin D deficiency has been linked with many diseases, including cardiovascular and neurological diseases, as well as with immune system function and its role during infections. An influence of vitamin D on the reproductive functions of women and men has been also reported. Endometriosis is one of the conditions responsible for infertility in women, and the contribution of vitamin D on the development of the disease has been investigated. Yet, a direct link between predisposition to endometriosis or severity of the disease and vitamin D status has not been defined. Some studies report no changes in vitamin D levels in endometriosis patients, compared to healthy controls, while others show a significant increase or decrease in vitamin D concentration in women suffering from endometriosis. Therefore, further studies are needed to establish the relationship between endometriosis and vitamin D status, which may be useful in designing vitamin D supplementation schedules for endometriosis patients, or in monitoring women at risk of developing the disease.

Vitamin D
Reproductive functions
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