IMR Press / CEOG / Volume 46 / Issue 4 / DOI: 10.12891/ceog4762.2019

Clinical and Experimental Obstetrics & Gynecology (CEOG) is published by IMR Press from Volume 47 Issue 1 (2020). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with S.O.G.

Open Access Original Research
A comparative study of three ultrasonic elastographic methods for the differentiation and diagnosis of benign and malignant breast masses
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1 Department of General Surgery, The First Affiliated Hospital of Medical College of Shihezi University, Shihezi, Xinjiang, China
2 Department of Function, The First Affiliated Hospital of Medical College of Shihezi University, Shihezi, Xinjiang, China
3 Department of Physiology and Pathophysiology, Medical College of Shihezi University, Shihezi, Xinjiang, China
4 Department of Statistics, Medical College of Shihezi University, Shihezi, Xinjiang, China
*Correspondence: guilinlu0031@126.com (JUN LI)
†Contributed equally.
Clin. Exp. Obstet. Gynecol. 2019, 46(4), 587–592; https://doi.org/10.12891/ceog4762.2019
Published: 10 August 2019
Abstract

Background: To evaluate the application of three elastography methods including real-time tissue elasticity imaging (RTE), strain rate ratio elasticity imaging (SR), and acoustic radiation force elastic imaging (ARFI) in two ultrasound instruments for the diagnosis of benign and malignant breast lesions. Materials and Methods: The authors examined 97 breast nodules of 97 patients who were ready to undergo adenomammectomy. For each patient, RTE was applied to determin nodule properties by level 5 score method, SR was applied to measure the strain rate ratio of targeted nodules, and the surrounding mammary glands at the same level, ARFI was applied to measure internal and marginal shear wave velocity (SWV) values of targeted nodules. Results: The sensitivity and specificity of RTE, SR, the internal SWV values, and marginal SWV values were more than 80% in diagnosing breast nodules. Area under the curve of RTE, SR, the internal SWV values, and the marginal SWV values in diagnosis of benign and malignant breast nodules were 0.923, 0.934, 0.934 and 0.916, respectively. No significant differences were found among the four values for the diagnosis efficiency. Conclusions: RTE, SR, and ARFI are all highly valuable in diagnosing benign and malignant breast nodules.

Keywords
Ultrasonic elastography
Breast masses
Real-time tissue elasticity imaging
Strain rate ratio elasticity imaging
Acoustic radiation force elastic imaging
Differential diagnosis
Figures
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