Purpose: To describe a second case of viability past the first trimester despite an inappropriate rise of the serum human chorionic gonadotropin (hCG) levels in the early pregnancy. Materials and Methods: A serum beta hCG level was obtained 17, 28, and 31 days after conception. Serial sonographic studies were performed throughout the first trimester and into the early second trimester. Results: The first serum hCG level at 17 days from conception was appropriate at 484 mIU/mL. The serum beta hCG level did not appropriately increase at 28 and 31 days (4, 844 and 9, 585 mIU/mL), respectively. Nevertheless fetal viability was seen on sonography throughout the first and early second trimesters She delivered a full-term healthy baby. Also for the first time a full-term delivery of a healthy baby from the first described case is reported (this case had only described surviving the first trimester. Conclusions: A delivery of a healthy baby despite inappropriate rising serial beta hCG levels is possible but rare.
Cite this article
Successful live delivery despite an inappropriate rise in the serial human chorionic gonadotropin level
1 Cooper Institute for Reproductive and Hormonal Disorders, P.C., Mt. Laurel, NJ, USA
2 Cooper Medical School of Rowan University, Department of Obstetrics and Gynecology, Division of Reproductive Endocrinology & Infertility, Camden, NJ, USA;
Clin. Exp. Obstet. Gynecol. 2019, 46(2), 297–298; https://doi.org/10.12891/ceog4708.2019
Published: 10 April 2019
Serial hCG levels