IMR Press / CEOG / Volume 46 / Issue 1 / DOI: 10.12891/ceog4319.2019

Clinical and Experimental Obstetrics & Gynecology (CEOG) is published by IMR Press from Volume 47 Issue 1 (2020). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with S.O.G.

Open Access Original Research
Screening for group B hemolytic streptococcal infection in pregnancy in a low-resourced country
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1 The University of the West Indies, St. Augustine Campus, Trinidad
2 Port-of-Spain General Hospital, Port-of-Spain, Trinidad
3 Westshore Medical Hospital, Port-of-Spain, Trinidad
4 San Fernando General Hospital, San Fernando, Trinidad
*Correspondence: bharath.bassaw@sta.uwi.edu (B. BASSAW)
Clin. Exp. Obstet. Gynecol. 2019, 46(1), 45–49; https://doi.org/10.12891/ceog4319.2019
Published: 10 February 2019
Abstract

Objectives: The objectives of this study conducted in a low-resourced country were to determine the feasibility and acceptability among pregnant women of universal screening for group B streptococcus (GBS), the prevalence of GBS, to calculate the risk of vertical transmission, and to study the neonatal outcome of early onset group B streptococcus disease (EOGBSD). Materials and Methods: All pregnant women between 35-37 weeks of gestation who attended the Port-of-Spain General Hospital during a six-month interval were enrolled in a study involving universal screening for group B streptococcus from vaginal and ano-rectal swabs. After appropriate laboratory preparation, inspection of the plate for GBS was performed. Patients found to be GBS screen-positive received intrapartum antibiotic prophylaxis (IAP). Results: Among the 420 eligible patients, 341 women (81.2%) agreed to participate. A total of 52 maternities (15.2%) were confirmed as GBS screen-positive. The highest rate of positive results were observed in Afro-Caribbean women, although this difference was not statistically significant (p > 0.05). Intrapartum antibiotic prophylaxis (IAP) was administered to 37 patients (71.1%). Conclusion: This study reveals that despite the relatively low prevalence rate of GBS, a policy of universal screening and IAP in low-resourced countries, it is possible to address the major burden of EOGBSD.

Keywords
Group B streptococcus
Neonatal sepsis
Screening
Antibiotic prophylaxis
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