Purpose of investigation: To assess three different types of hysterectomies for benign pathology at Vilnius University Hospital Santaros Klinikos (VUH SK). Materials and Methods: The medical records of 1361 patients who underwent hysterectomy for benign pathology at the Centre of Obstetrics and Gynecology Vilnius University Hospital Santaros Klinikos between January 1, 2010 and December 31, 2016 were retrospectively reviewed. The comparison was made by evaluating the following data: patients’ age, indications of surgery, operating time, blood loss, hospital stay, uterine size, histological analysis, and complications. Data was considered statistically significant when p-value was less than 0.05. Results: During the study period, 1,361 hysterectomies were performed (vaginal hysterectomy - 41% (n=552), laparoscopic hysterectomy - 30% (n=413), and abdominal hysterectomy - 29% (n=396). Mean age of the patients was 55 ± 12 years. In vaginal hysterectomy group patients were significantly older. Uterine size was larger in abdominal and laparoscopic hysterectomy groups. Operating time was longer using the laparoscopic route than the abdominal or vaginal. The mean blood loss was lowest in laparoscopic hysterectomy group compared with the other groups. The shortest hospital stay was also in the laparoscopic group. Conclusion: The laparoscopic hysterectomies have the shortest hospital stays and the lowest blood loss in comparison with abdominal and vaginal groups. Abdominal and vaginal hysterectomies are shorter, however, the duration of laparoscopic hysterectomies is becoming shorter annually. The complications’ rates between groups do not differ significantly.