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Original Research
The correlation of maternal serum and cord blood copeptin levels with intrapartum fetal distress
İ. Ulu1, *, Y. Çekmez1, M.S. Gülşen1, E. T. Haberal1, E.E. Yoğurtçuoğlu1, S.B. Türkmen1, B. Sunar2, G. Kıran1
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1
Department of Obstetrics and Gynecology, Medical Sciences University İstanbul Ümraniye Medical and Research Hospital, Istanbul, Turkey
2
Department of Biochemistry, Fatih Sultan Mehmet Medical and Research Hospital, Istanbul, Turkey
Clin. Exp. Obstet. Gynecol. 2018, 45(6), 871–874;
https://doi.org/10.12891/ceog4275.2018
Published: 10 December 2018
Abstract
Aim: Fetal distress (FD) is mostly an important sign of fetal hypoxia. The hypothalamic-pituitary-adrenal axis is an important limb of acute stress response. Copeptin is a hormone of endogenous stress. The authors aimed to investigate whether the level of copeptin correlates with FD or not. Material and Methods: Twenty-four pregnant women and their babies with the diagnosis of FD confirmed by category III fetal heart rate (FHR) pattern were compared with 20 uncomplicated pregnant women and their babies who were delivered by elective cesarean section. Results: The mean maternal serum copeptin level showed no significant difference between the mothers of control group and the mothers of FD group (p > 0.05). The mean umbilical cord serum copeptin level showed no significant difference between the groups (p > 0.05). Conclusion: The authors revealed that copeptin is not correlated with the presence of FD, thus further studies are needed to discover new biomarkers.
Keywords
Biomarker
Copeptin
Fetal distress
Vasopressin